Title : Impaired pentose phosphate pathway in the development of 3D MCF-7 cells mediated intracellular redox disturbance and multi-cellular resistance without drug induction.

Pub. Date : 2018 May

PMID : 29291545






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Impaired PPP disturbed redox-cycling, generated reactive oxygen species (ROS), which triggered cell cycle arrest and caused the switch to Chk2/p53/NF-kappaB pathway-mediated P-gp induction. Reactive Oxygen Species phosphoglycolate phosphatase Homo sapiens
2 Impaired PPP disturbed redox-cycling, generated reactive oxygen species (ROS), which triggered cell cycle arrest and caused the switch to Chk2/p53/NF-kappaB pathway-mediated P-gp induction. Reactive Oxygen Species phosphoglycolate phosphatase Homo sapiens