Title : The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer.

Pub. Date : 2017

PMID : 29281678






1 Functional Relationships(s)
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1 We have previously shown that TNBCs are active for oncogenic Wnt10b/beta-catenin signaling and that WNT10B ligand and its downstream target HMGA2 are predictive of poorer outcomes and are strongly associated with chemoresistant TNBC metastatic disease. tnbcs Wnt family member 10B Homo sapiens