Pub. Date : 2018 Jan
PMID : 29269566
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Further analysis demonstrated that treatment with Bortezomib sensitized TC cells to Vemurafenib via mitochondrial dysregulation and apoptosis of TC cells, as evidenced by the increase in the expression of p53, Noxa protein, the loss of mitochondrial membrane potential, cytochrome c release and Poly (ADP-ribose) polymerase cleavage. | Bortezomib | tumor protein p53 | Homo sapiens |