Title : Oxidative stress-mediated p53/p21WAF1/CIP1 pathway may be involved in microcystin-LR-induced cytotoxicity in HepG2 cells.

Pub. Date : 2018 Mar

PMID : 29248874






1 Functional Relationships(s)
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1 Biochemical assays revealed that MC-LR exposure altered the protein levels of HSP70 and HSP90, generally inhibited superoxide dismutase and catalase, reduced glutathione content, and increased the cellular malondialdehyde level of HepG2 cells, suggesting that MC-LR may induce biochemical disturbance and oxidative stress in HepG2 cells. cyanoginosin LR heat shock protein 90 alpha family class A member 1 Homo sapiens