Title : Curcumin enhances liver SIRT3 expression in the rat model of cirrhosis.

Pub. Date : 2017 Dec

PMID : 29238464






2 Functional Relationships(s)
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1 Results: It was identified that SIRT3, AMPK, CPT-1A, IDH2 and MnSOD expression significantly decreased in BDL rats compared to sham rats; however, in the curcumin treatment of BDL rats, the expression of these factors increased significantly compared to BDL (P<0.05). Curcumin superoxide dismutase 2 Rattus norvegicus
2 Conclusion: Curcumin reduced liver damage and oxidative stress in the liver tissue of BDL rats through up-regulation of SIRT3, AMPK, CPT-1A, IDH2 and MnSOD as well as changing the level of serum lipid profile. Curcumin superoxide dismutase 2 Rattus norvegicus