Title : MicroRNA-486-5p suppresses TGF-β2-induced proliferation, invasion and epithelial-mesenchymal transition of lens epithelial cells by targeting Smad2.

Pub. Date : 2017 Dec

PMID : 29229876






1 Functional Relationships(s)
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1 In short, these data show that miR-486-5p overexpression can inhibit TGF-beta2-induced proliferation, invasion and EMT in SRA01/04 cells by repressing Smad2/Smad3 signalling, implying that miR-486-5p may be an effective target to interfere in the progression of PCO. mir-486 SMAD family member 3 Homo sapiens