Pub. Date : 2019 Mar
PMID : 29228766
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND/AIMS: This study was performed to determine whether adding coenzyme Q10 (CoQ10) to metformin (MET) has a beneficial effect as a treatment for sirolimus (SRL)-induced diabetes mellitus (DM). | coenzyme Q10 | MET proto-oncogene, receptor tyrosine kinase | Rattus norvegicus |
| 2 | The addition of CoQ10 to MET further improved hyperglycemia, decreased HOMA-R index, and increased plasma insulin concentration compared with the SRL group than MET alone therapy. | coenzyme Q10 | MET proto-oncogene, receptor tyrosine kinase | Rattus norvegicus |
| 3 | In addition, co-treatment of CoQ10 and MET significantly increased the levels of antiperoxidative enzymes in the pancreas islet cells compared with MET. | coenzyme Q10 | MET proto-oncogene, receptor tyrosine kinase | Rattus norvegicus |