Pub. Date : 2016 Mar-Apr
PMID : 29227599
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have studied hypoxic regulation of the expression of genes encoded GADD (growth arrest and DNAdamage) family proteins in U87 glioma cells in relation to inhibition of IRE1 (inositol requiring enzyme-1),which controls cell proliferation and tumor growth as a central mediator of endoplasmic reticulum stress.We have shown that hypoxia up-regulates the expression of GADD34, GADD45A, GADD45B, and GADD153genes, which are related to cell proliferation and apoptosis, in control (transfected by empty vector) gliomacells in gene specific manner. | gadd | protein phosphatase 1 regulatory subunit 15A | Homo sapiens |