Title : Hyperpolarization of amino acid derivatives in water for biological applications.

Pub. Date : 2015 Jul 1

PMID : 29218193






1 Functional Relationships(s)
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1 We report on the successful synthesis and hyperpolarization of N-unprotected alpha-amino acid ethyl propionate esters and extensively, on an alanine derivative hyperpolarized by PHIP (4.4 +- 1.0% 13C-polarization), meeting required levels for in vivo detection. alpha-amino acid ethyl propionate esters pleckstrin homology domain interacting protein Homo sapiens