Title : Inhibition of autophagy enhances the targeted therapeutic effect of sorafenib in thyroid cancer.

Pub. Date : 2018 Feb

PMID : 29207150






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Western blotting results indicated that sorafenib concurrently inhibited the activities of the MAPK and AKT/mTOR pathways in thyroid cancer. Sorafenib AKT serine/threonine kinase 1 Homo sapiens
2 Autophagy was activated by sorafenib in thyroid cancer, both in vitro and in vivo, which was at least in part due to suppression of the AKT/mTOR pathway. Sorafenib AKT serine/threonine kinase 1 Homo sapiens