Title : Epigallocatechin-3-gallate enhances differentiation of acute promyelocytic leukemia cells via inhibition of PML-RARĪ± and HDAC1.

Pub. Date : 2018 Mar

PMID : 29193405






3 Functional Relationships(s)
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1 EGCG (100 muM) significantly inhibited proliferation and induced apoptosis in HL-60 and NB4 cells. epigallocatechin gallate latexin Homo sapiens
2 EGCG, at 25 muM concentration, induced differentiation of leukemic cells towards granulocytic pattern in a similar manner to that observed for ATRA (1 muM). epigallocatechin gallate latexin Homo sapiens
3 EGCG, at 25 muM concentration, induced differentiation of leukemic cells towards granulocytic pattern in a similar manner to that observed for ATRA (1 muM). epigallocatechin gallate latexin Homo sapiens