Pub. Date : 2018 Feb
PMID : 29193067
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that kainic acid-induced SNO-GluK2 is mediated by GluK2 itself, regulated by neuronal nitric oxide synthase (nNOS) and the level of cytoplasmic calcium in vivo and in vitro hippocampus neurons. | Kainic Acid | glutamate ionotropic receptor kainate type subunit 2 | Rattus norvegicus |
| 2 | Here, we report that kainic acid-induced SNO-GluK2 is mediated by GluK2 itself, regulated by neuronal nitric oxide synthase (nNOS) and the level of cytoplasmic calcium in vivo and in vitro hippocampus neurons. | Kainic Acid | glutamate ionotropic receptor kainate type subunit 2 | Rattus norvegicus |
| 3 | Moreover, immunohistochemistry staining results showed that inhibition of SNO-GluK2 by blocking nNOS or GluK2 or by reducing the level of cytoplasmic calcium-protected hippocampal neurons from kainic acid-induced injury. | Kainic Acid | glutamate ionotropic receptor kainate type subunit 2 | Rattus norvegicus |