Title : Design, synthesis, biological evaluation and molecular modeling of novel 2-amino-4-(1-phenylethoxy) pyridine derivatives as potential ROS1 inhibitors.

Pub. Date : 2018 Jan 1

PMID : 29174814






1 Functional Relationships(s)
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1 It also gave a probable molecular explanation for their activity and selectivity, which the methoxyl group in benzene ring was the crucial to the selectivity to ROS1 versus ALK. Benzene ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens