Title : Specific binding of human C-reactive protein towards supported monolayers of binary and engineered phospholipids.

Pub. Date : 2018 Jan 1

PMID : 29172154






3 Functional Relationships(s)
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1 We have shown previously the calcium-independent adsorption of CRP toward 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and lysophosphatidylcholine (LPC) on supported phospholipid monolayers. Calcium C-reactive protein Homo sapiens
2 CRP recognized 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine (POPS) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1"-rac-glycerol) (POPG) in the supported POPC monolayers without calcium at pH 7.4 and 5.5. Calcium C-reactive protein Homo sapiens
3 Calcium-dependent CRP binding was observed only at pH 5.5 on supported monolayers of engineered phospholipids with inverted headgroups relative to POPC. Calcium C-reactive protein Homo sapiens