Title : The protective effect of phloretin in osteoarthritis: an in vitro and in vivo study.

Pub. Date : 2018 Jan 24

PMID : 29168867

1 Functional Relationships(s)
Compound Name
Protein Name
1 In this study, we found that phloretin significantly inhibited the IL-1beta-induced production of NO, PGE2, TNF-alpha, and IL-6, the expression of COX-2, iNOS, MMP-3, MMP-13, and ADAMTS-5, and the degradation of aggrecan and collagen-II in human OA chondrocytes. Dinoprostone interleukin 1 beta Homo sapiens