Pub. Date : 2018 Jan 1
PMID : 29162452
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DT-13 ameliorates TNF-alpha-induced nitric oxide production in the endothelium in vivo and in vitro. | Nitric Oxide | tumor necrosis factor | Homo sapiens |
2 | This study aimed to explore the protective effect of DT-13 on endothelium through regulating of nitric oxide production induced by Tumor necrosis factor-alpha (TNF-alpha). | Nitric Oxide | tumor necrosis factor | Homo sapiens |
3 | This study aimed to explore the protective effect of DT-13 on endothelium through regulating of nitric oxide production induced by Tumor necrosis factor-alpha (TNF-alpha). | Nitric Oxide | tumor necrosis factor | Homo sapiens |
4 | Enzyme-linked immunosorbent assay (ELISA) results demonstrated that DT-13 could suppress the TNF-alpha-induced upregulation of reactive oxygen species (ROS), tumor necrosis factor receptor (TNFR), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1) and nitric oxide in vivo dose-dependently and suppressed production of nitric oxide in vitro as shown by DAF-FMDA. | Nitric Oxide | tumor necrosis factor | Homo sapiens |
5 | Enzyme-linked immunosorbent assay (ELISA) results demonstrated that DT-13 could suppress the TNF-alpha-induced upregulation of reactive oxygen species (ROS), tumor necrosis factor receptor (TNFR), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1) and nitric oxide in vivo dose-dependently and suppressed production of nitric oxide in vitro as shown by DAF-FMDA. | Nitric Oxide | tumor necrosis factor | Homo sapiens |