Title : PKB/Akt and MAPK/ERK phosphorylation is highly induced by inositols: Novel potential insights in endothelial dysfunction in preeclampsia.

Pub. Date : 2017 Oct

PMID : 29153661






8 Functional Relationships(s)
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1 PKB/Akt and MAPK/ERK phosphorylation is highly induced by inositols: Novel potential insights in endothelial dysfunction in preeclampsia. Inositol AKT serine/threonine kinase 1 Homo sapiens
2 PKB/Akt and MAPK/ERK phosphorylation is highly induced by inositols: Novel potential insights in endothelial dysfunction in preeclampsia. Inositol AKT serine/threonine kinase 1 Homo sapiens
3 To evaluate the pathophysiological significance of this response, the effect of myo-inositol and d-chiro inositol on the activation of PKB/Akt and MAPK/ERK was assessed in human endothelial cells in vitro. Inositol AKT serine/threonine kinase 1 Homo sapiens
4 To evaluate the pathophysiological significance of this response, the effect of myo-inositol and d-chiro inositol on the activation of PKB/Akt and MAPK/ERK was assessed in human endothelial cells in vitro. Inositol AKT serine/threonine kinase 1 Homo sapiens
5 Both inositols promoted a significantly higher PKB/Akt and MAPK/ERK phosphorylation than insulin. Inositol AKT serine/threonine kinase 1 Homo sapiens
6 Both inositols promoted a significantly higher PKB/Akt and MAPK/ERK phosphorylation than insulin. Inositol AKT serine/threonine kinase 1 Homo sapiens
7 Thus, exogenously administered inositols can activate PKB/Akt and MAPK/ERK in human endothelial cells in vitro. Inositol AKT serine/threonine kinase 1 Homo sapiens
8 Thus, exogenously administered inositols can activate PKB/Akt and MAPK/ERK in human endothelial cells in vitro. Inositol AKT serine/threonine kinase 1 Homo sapiens