Title : Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis.

Pub. Date : 2018 Mar

PMID : 29133078






3 Functional Relationships(s)
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1 A similar shift in the composition of the fecal microbiota occurred after a few months in TG mice heterozygous for REG3A that harbored a wild-type maternal microbiota at birth; these mice developed less-severe forms of colitis following DSS administration. dss regenerating islet-derived 3 alpha Mus musculus
2 Cohoused and germ-free mice fed feces from REG3A-TG mice and given DSS developed less-severe forms of colitis and had reduced lipopolysaccharide activation of the toll-like receptor 4 and increased survival times compared with mice not fed feces from REG3A-TG mice. dss regenerating islet-derived 3 alpha Mus musculus
3 Fecal samples from REG3A-TG mice had lower levels of ROS than feces from control mice during DSS administration. dss regenerating islet-derived 3 alpha Mus musculus