Title : Activating prostaglandin E2 receptor subtype EP4 increases secreted mucin from airway goblet cells.

Pub. Date : 2018 Feb

PMID : 29129801






2 Functional Relationships(s)
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1 PGE2 secretion is increased in the airways of patients with asthma by secretory phospholipases A2, which also increases MUC5AC mucin in goblet cells. Dinoprostone mucin 5AC, oligomeric mucus/gel-forming Homo sapiens
2 We hypothesized that PGE2 would also increase MUC5AC mRNA and secreted protein through specific EP receptor activation. Dinoprostone mucin 5AC, oligomeric mucus/gel-forming Homo sapiens