Title : Wip1 regulates blood-brain barrier function and neuro-inflammation induced by lipopolysaccharide via the sonic hedgehog signaling signaling pathway.

Pub. Date : 2018 Jan

PMID : 29128669






1 Functional Relationships(s)
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1 Additionally, activating or inhibiting the SHH pathway by purmorphamine or cyclopamine, respectively, abolished the Wip1-induced changes in transepithelial electrical resistance and permeability and inflammatory responses in the LPS-injured BBB model. purmorphamine sonic hedgehog signaling molecule Homo sapiens