Title : Rethinking mercury: the role of selenium in the pathophysiology of mercury toxicity.

Pub. Date : 2018 May

PMID : 29124976






1 Functional Relationships(s)
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1 A number of other important possible target selenoproteins have been identified, including selenoprotein P, K, and T. Impairment of the thioredoxin and glutaredoxin systems allows for proliferation intracellular reactive oxygen species which leads to glutamate excitosis, calcium dyshomeostasis, mitochondrial injury/loss, lipid peroxidation, impairment of protein repair, and apoptosis. Reactive Oxygen Species thioredoxin Homo sapiens