Title : Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro.

Pub. Date : 2018 Jun

PMID : 29124635






2 Functional Relationships(s)
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1 Atropisomers of 2,2",3,3",6,6"-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro. 2,3,6,2',3',6'-hexachlorobiphenyl pyruvate carboxylase Homo sapiens
2 PCB136 atropisomers were found to exert differential effects on estrogen receptor (ER) activation; (+)-PCB 136 was estrogenic, while (-)-PCB 136 was antiestrogenic. 2,3,6,2',3',6'-hexachlorobiphenyl pyruvate carboxylase Homo sapiens