Title : Critical Study of the Recognition between C-Reactive Protein and Surface-Immobilized Phosphorylcholine by Quartz Crystal Microbalance with Dissipation.

Pub. Date : 2018 Jan 23

PMID : 29120646






7 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 C-reactive protein (CRP), a biomarker for cardiovascular disease, has been reported to have a strong affinity to zwitterionic phosphorylcholine (PC) groups in the presence of calcium ions. Phosphorylcholine C-reactive protein Homo sapiens
2 C-reactive protein (CRP), a biomarker for cardiovascular disease, has been reported to have a strong affinity to zwitterionic phosphorylcholine (PC) groups in the presence of calcium ions. Phosphorylcholine C-reactive protein Homo sapiens
3 By appropriately using the features of PC-immobilized surfaces, including specific recognition to CRP and nonfouling surface, it is reasonable to create an antibody-free biosensor for the specific capture of CRP. Phosphorylcholine C-reactive protein Homo sapiens
4 By appropriately using the features of PC-immobilized surfaces, including specific recognition to CRP and nonfouling surface, it is reasonable to create an antibody-free biosensor for the specific capture of CRP. Phosphorylcholine C-reactive protein Homo sapiens
5 The specific interaction of CRP with PC groups was monitored by using a quartz crystal microbalance with dissipation (QCM-D). Phosphorylcholine C-reactive protein Homo sapiens
6 Notably, the dissipation energy also dropped during the binding process between CRP and PC, indicating the release of water molecules from the PC groups during CRP adsorption. Phosphorylcholine C-reactive protein Homo sapiens
7 Notably, the dissipation energy also dropped during the binding process between CRP and PC, indicating the release of water molecules from the PC groups during CRP adsorption. Phosphorylcholine C-reactive protein Homo sapiens