Title : Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors.

Pub. Date : 2017 Nov 8

PMID : 29119917






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 METHODS: Unlike human purine nucleoside phosphorylase (PNP), E. coli PNP accepts adenine containing nucleosides as substrates, and is therefore able to selectively activate non-toxic purine analogs in tumor tissue. Nucleosides purine nucleoside phosphorylase Homo sapiens