Title : Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems.

Pub. Date : 2017 Oct 6

PMID : 29113345






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The Raf inhibitor sorafenib (SFN) or the Mek inhibitor U0126 suppressed MAPK signaling to a greater extent than LPN; which correlated with greater cytotoxic potency of SFN, but not U0126. Sorafenib zinc fingers and homeoboxes 2 Homo sapiens
2 The Raf inhibitor sorafenib (SFN) or the Mek inhibitor U0126 suppressed MAPK signaling to a greater extent than LPN; which correlated with greater cytotoxic potency of SFN, but not U0126. Sorafenib zinc fingers and homeoboxes 2 Homo sapiens
3 The Raf inhibitor sorafenib (SFN) or the Mek inhibitor U0126 suppressed MAPK signaling to a greater extent than LPN; which correlated with greater cytotoxic potency of SFN, but not U0126. Sorafenib zinc fingers and homeoboxes 2 Homo sapiens