Title : miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer.

Pub. Date : 2017 Nov

PMID : 29113199






1 Functional Relationships(s)
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1 The cells transfected with a miR-214 inhibitor exhibited significantly upregulated PTEN expression and significantly downregulated phosphatidylinositol (3,4,5)-trisphosphate (PIP3), phosphorylated (p)-Akt and p-glycogen synthase kinase (GSK)-3beta expression. phosphatidylinositol 3,4,5-triphosphate microRNA 214 Homo sapiens