Pub. Date : 2018 Jan
PMID : 29101808
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Gastrodin reduces IL-1beta-induced apoptosis, inflammation, and matrix catabolism in osteoarthritis chondrocytes and attenuates rat cartilage degeneration in vivo. | gastrodin | interleukin 1 beta | Rattus norvegicus |
2 | Our results showed that gastrodin could prevent chondrocyte apoptosis induced by IL-1beta. | gastrodin | interleukin 1 beta | Rattus norvegicus |
3 | Additionally, gastrodin suppressed the nuclear factor kappa B (NF-kappaB) pathway, decreased the release of inflammatory mediators (IL-6, TNF-alpha), and reduced matrix catabolism in IL-1beta-treated chondrocytes. | gastrodin | interleukin 1 beta | Rattus norvegicus |