Title : Spermine oxidase promotes bile canalicular lumen formation through acrolein production.

Pub. Date : 2017 Nov 1

PMID : 29093526






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Spermine oxidase promotes bile canalicular lumen formation through acrolein production. Acrolein spermine oxidase Homo sapiens
2 Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H2O2) and 3-aminopropanal, which is spontaneously converted to acrolein. Acrolein spermine oxidase Homo sapiens
3 Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H2O2) and 3-aminopropanal, which is spontaneously converted to acrolein. Acrolein spermine oxidase Homo sapiens
4 Our results suggest that SMOX plays a central role in the formation of bile canalicular lumen in liver cells by activating Akt pathway through acrolein production. Acrolein spermine oxidase Homo sapiens