Title : Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.

Pub. Date : 2017 Oct 31

PMID : 29089425






1 Functional Relationships(s)
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1 KPC-2 is a beta-lactamase that inactivates carbapenems and beta-lactamase inhibitors (e.g., clavulanate) and is prevalent around the world, including in the United States. Clavulanic Acid KPC-2 Escherichia coli