Title : Molecular docking analysis of aplysin analogs targeting survivin protein.

Pub. Date : 2017

PMID : 29081608






1 Functional Relationships(s)
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1 Molecular docking results revealed that analog (AP 4) of Aplysin, showed very promising inhibitory potential against survivin with a binding energy of -8.75 kcal/mol and Ki 388.28 nM as compared to its known inhibitor, Celecoxib having binding energy of -6.65 kcal/mol and Ki 13.43 muM. Celecoxib transcription factor AP-4 Homo sapiens