Pub. Date : 1988 Mar
PMID : 2908045
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine was shown to produce significant increases in plasma AVP from 1.7 +/- 0.4 to 75.3 +/- 35.1 pg/ml (P less than .05) and in plasma ANF levels from 39 +/- 11 to 121 +/- 52 pg/ml (P less than .05) within 5 min of an i.v. | Nicotine | vasopressin-neurophysin 2-copeptin | Oryctolagus cuniculus |
| 2 | The increase in ANF plasma concentrations was probably due to a primary response to nicotine, for although exogenous AVP (1 microgram i.v.) | Nicotine | vasopressin-neurophysin 2-copeptin | Oryctolagus cuniculus |
| 3 | It was concluded that nicotine stimulates the secretion of AVP by activating central nicotinic projections to the hypothalamus. | Nicotine | vasopressin-neurophysin 2-copeptin | Oryctolagus cuniculus |