Title : Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer.

Pub. Date : 2017 Nov

PMID : 29078883






1 Functional Relationships(s)
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1 In a murine breast cancer model, sphingosine kinase 1, S1P receptor 1, interleukin 6, and STAT3 were overexpressed in the doxorubicin-treated group, whereas all of them were significantly suppressed with addition of FTY720. Doxorubicin sphingosine kinase 1 Mus musculus