Title : Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer.

Pub. Date : 2018 Feb 8

PMID : 29059155






1 Functional Relationships(s)
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1 Blocking lipid/cholesterol synthesis in AR variants-expressing CRPC cell line and xenograft models markedly reduces tumor growth through inhibition of mTOR pathway. Cholesterol androgen receptor Homo sapiens