Title : Vortioxetine exerts anti-inflammatory and immunomodulatory effects on human monocytes/macrophages.

Pub. Date : 2018 Jan

PMID : 29057467






1 Functional Relationships(s)
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1 KEY RESULTS: Vortioxetine significantly reduced the PMA-induced oxidative burst in monocytes and in macrophages (M1 and M2), causing a concomitant shift of macrophages from the M1 to the M2 phenotype, demonstrated by a significant decrease in the expression of the surface marker CD86 and an increase in CD206. Vortioxetine mannose receptor C-type 1 Homo sapiens