Pub. Date : 1987
PMID : 2905532
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | N1-([11C]-Methyl)-2-Br-LSD ([11C]-MBL) has been developed as a positron emission tomography (PET) imaging agent for serotonin 5-HT2 receptors. | Carbon-11 | mannose-binding lectin family member 3, pseudogene | Homo sapiens |
2 | Intravenous injection of [11C]-MBL in a baboon led to selective labeling of cortical regions that was markedly blocked by prior administration of ketanserin, a selective 5-HT2 receptor antagonist. | Carbon-11 | mannose-binding lectin family member 3, pseudogene | Homo sapiens |
3 | Clinical trials with [11C]-MBL have been conducted in seven normal human volunteers, and the regional distribution of radioactivity in the brain was distinctly serotonergic. | Carbon-11 | mannose-binding lectin family member 3, pseudogene | Homo sapiens |
4 | These studies indicate that [11C]-MBL is a selective radioligand that can be used to monitor serotonin 5-HT2 receptor densities in vivo in most regions of the human brain. | Carbon-11 | mannose-binding lectin family member 3, pseudogene | Homo sapiens |