Title : Development of a Modular Synthetic Route to (+)-Pleuromutilin, (+)-12-epi-Mutilins, and Related Structures.

Pub. Date : 2017 Nov 15

PMID : 29048164






1 Functional Relationships(s)
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Protein Name
Organism
1 The eneimide 57 was employed in a 2-fold neopentylic coupling reaction with an organolithium reagent derived from the alkyl iodides (R)- or (S)-30, which contain the C11-C13 atoms of the target, to provide diastereomeric diketones in 60% or 48% yield (for coupling with (R)- or (S)-30, respectively). diketones RNA polymerase III subunit K Homo sapiens