Title : Structural Basis of Inhibition of ERĪ±-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides.

Pub. Date : 2017 Nov 9

PMID : 29045135






1 Functional Relationships(s)
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1 Here, we report the co-crystal structure of a helical peptide stabilized by a N-terminal unnatural cross-linked aspartic acid (TD) in complex with the ERalpha ligand binding domain (LBD). Aspartic Acid estrogen receptor 1 Homo sapiens