Title : In an in-vitro model using human fetal membranes, 17-α hydroxyprogesterone caproate is not an optimal progestogen for inhibition of fetal membrane weakening.

Pub. Date : 2017 Dec

PMID : 29031893






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1 In a previous report, we demonstrated that 3 progestogens, progesterone, 17-alpha hydroxyprogesterone (17-OHP), and medroxyprogesterone acetate (MPA), each inhibit both TNF-alpha- and thrombin-induced fetal membrane weakening at 2 distinct points of the fetal membrane weakening pathway. Progesterone tumor necrosis factor Homo sapiens