Title : Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient.

Pub. Date : 2018 Jan

PMID : 29024690






2 Functional Relationships(s)
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1 Our objective was to determine the properties of the sodium current in iPS-CM with a mutation in SCN5A associated with Brugada syndrome. IPS sodium voltage-gated channel alpha subunit 5 Homo sapiens
2 Dermal fibroblasts from a Brugada syndrome patient with a mutation in SCN5A (c.1100G>A, leading to Nav1.5_p.R367H) were reprogrammed to iPS cells. IPS sodium voltage-gated channel alpha subunit 5 Homo sapiens