Title : Naloxone excites oxytocin neurones in the supraoptic nucleus of lactating rats after chronic morphine treatment.

Pub. Date : 1988 Feb

PMID : 2900890






2 Functional Relationships(s)
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1 Concentrations in plasma of vasopressin, measured by radioimmunoassay in samples of femoral arterial blood, rose in morphine-treated rats from 7.4 +/- 2.4 to 29.2 +/- 3.7 pg/ml after naloxone, but did not rise significantly in control rats. Morphine arginine vasopressin Rattus norvegicus
2 The firing activity of five phasic (putative vasopressin) supraoptic neurones in morphine-treated rats was increased for at least 30 min by the injection of naloxone; these increases were the result of a raised intraburst firing rate with no change in burst duration or frequency. Morphine arginine vasopressin Rattus norvegicus