Pub. Date : 2018 Jan 1
PMID : 28988972
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arginine vasopressin antagonizes the effects of prostaglandin E2 on the spontaneous activity of warm-sensitive and temperature-insensitive neurons in the medial preoptic area in rats. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 2 | AVP attenuated the inhibitory effect of PGE2 on warm-sensitive neurons, and reversed the excitatory effect of PGE2 on low-slope temperature-insensitive neurons, demonstrating that AVP antagonized the effects of PGE2 on the spontaneous activity of these neurons. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 3 | We also demonstrated that AVP attenuated the PGE2-induced decrease in the prepotential"s rate of rise in warm-sensitive neurons and the PGE2-induced increase in that in low-slope temperature-insensitive neurons through the V1a receptor. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 4 | We also demonstrated that AVP attenuated the PGE2-induced decrease in the prepotential"s rate of rise in warm-sensitive neurons and the PGE2-induced increase in that in low-slope temperature-insensitive neurons through the V1a receptor. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 5 | Together, these data indicated that AVP antagonized the PGE2-induced change in the spontaneous activity of warm-sensitive and low-slope temperature-insensitive neurons in the MPO partly by reducing the PGE2-induced change in the prepotential of these neurons in a V1a receptor-dependent manner. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 6 | Together, these data indicated that AVP antagonized the PGE2-induced change in the spontaneous activity of warm-sensitive and low-slope temperature-insensitive neurons in the MPO partly by reducing the PGE2-induced change in the prepotential of these neurons in a V1a receptor-dependent manner. | Dinoprostone | arginine vasopressin | Rattus norvegicus |