Title : Permeant-specific gating of connexin 30 hemichannels.

Pub. Date : 2017 Dec 8

PMID : 28982982






2 Functional Relationships(s)
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1 Using the substituted cysteine accessibility method (SCAM), we evaluated the role of possible pore-lining residues in the permeation of ions and ethidium through Cx30 hemichannels. Ethidium gap junction protein beta 1 L homeolog Xenopus laevis
2 Of the cysteine-substituted residues, interaction of a proposed pore-lining cysteine at position 37 with the positively charged compound [2-(trimethylammonium)ethyl] methane thiosulfonate bromide (MTS-ET) increased Cx30-mediated currents with unperturbed ethidium permeability. Ethidium gap junction protein beta 1 L homeolog Xenopus laevis