Title : Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes.

Pub. Date : 2017 Nov

PMID : 28981125






1 Functional Relationships(s)
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1 In this protocol, unprotected peptide fragments are prepared by Fmoc solid-phase synthesis and coupled in aqueous buffers via native chemical ligation (NCL; in NCL, a peptide bond is formed between a peptide with an N-terminal Cys and another peptide having a C-terminal thioester). Cysteine nucleolin Homo sapiens