Title : A unique methylation pattern co-segregates with neural tube defect statuses in Han Chinese pedigrees.

Pub. Date : 2017 Dec

PMID : 28980068






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 A unique methylation pattern co-segregated with affected status: NTD cases had more hypermethylated than hypomethylated CpG islands; genes with different methylations clustered in pathways associated with epithelial-to-mesenchymal transition (ZEB2, SMAD6, and CDH23), folic acid/homocysteine metabolism (MTHFD1L), transcription/nuclear factors (HDAC4, HOXB7, SOX18), cell migration/motility/adhesion, insulin and cell growth, and neuron/axon development. Folic Acid fuzzy planar cell polarity protein Homo sapiens