Title : Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway.

Pub. Date : 2017

PMID : 28979810






2 Functional Relationships(s)
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1 It was found that chemotherapy drugs, such as epirubicin (EPB) and mitomycin C (MMC), effectively blocked expression of PcG in p53-wild-type HepG2 cells but not in PLC/PRF5 and Hep3B cells with p53 mutation or deletion. Epirubicin tumor protein p53 Homo sapiens
2 It was found that chemotherapy drugs, such as epirubicin (EPB) and mitomycin C (MMC), effectively blocked expression of PcG in p53-wild-type HepG2 cells but not in PLC/PRF5 and Hep3B cells with p53 mutation or deletion. Epirubicin tumor protein p53 Homo sapiens