Title : Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases.

Pub. Date : 2017 Dec

PMID : 28971874






1 Functional Relationships(s)
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1 MPC-1 selectively inhibits class C beta-lactamases, such as P99, by forming a nonhydrolyzable acyl adduct, and its inhibitory potency is ~2 to 5 times higher than that for clinically used beta-lactamase inhibitors clavulanate and sulbactam. Clavulanic Acid protein phosphatase 1 regulatory subunit 10 Homo sapiens