Title : Reduction in delay discounting due to nicotine and its attenuation by cholinergic antagonists in Lewis and Fischer 344 rats.

Pub. Date : 2018 Jan

PMID : 28971227

1 Functional Relationships(s)
Compound Name
Protein Name
1 RATIONALE: Nicotine acts as an agonist for nicotinic acetylcholine receptors (nAChRs), and mecamylamine, a nonselective nAChR antagonist, attenuates effects of nicotine on delay discounting in some rat strains; whether nicotine"s attenuation is specific to nAChR antagonism is unknown. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus