Title : Upregulation of cyclin-dependent kinase inhibitors CDKN1B and CDKN1C in hepatocellular carcinoma-derived cells via goniothalamin-mediated protein stabilization and epigenetic modifications.

Pub. Date : 2015

PMID : 28962365






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Alternatively, in TP53- and RB1-negative Hep-3B cells, GTN increased CDKN1C transcription and its subsequent translation by acting as a histone deacetylase inhibitor. goniothalamin tumor protein p53 Homo sapiens