Title : Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach.

Pub. Date : 2017 Oct

PMID : 28950208






2 Functional Relationships(s)
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1 Hence, the aim of the present study was to investigate the molecular mechanism of pelargonidin"s action on cell cycle regulators CDK1, CDK4, and CDK6 as well as the substrate-binding domain of DNMT1 and DNMT3A, which regulate the epigenetic signals related to DNA methylation. pelargonidin DNA methyltransferase 3 alpha Homo sapiens
2 In this context, pelargonidin may also inhibit the recognition of DNA and catalytic binding by DNMT1 and DNMT3A. pelargonidin DNA methyltransferase 3 alpha Homo sapiens