Title : Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide.

Pub. Date : 2017 Oct 15

PMID : 28943245






2 Functional Relationships(s)
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1 Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide. Acetazolamide carbonic anhydrase 9 Homo sapiens
2 For Human Carbonic Anhydrase IX (HCA IX) the dissociation constant of AZM was 3nM, whereas that of the 4-C10L17-AZM conjugate was 90pM, a 33-fold affinity enhancement. Acetazolamide carbonic anhydrase 9 Homo sapiens